Niacin (Vitamin B3)

Plain-language research summary.

DetailDoseFormsDeliveryEvidenceReferencesSafety
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Detail

lipidenergyskin

Supports NAD+ metabolism; high-dose forms used for lipid modulation.

Common Dietary Sources
  • Meat, fish, peanuts, fortified grains
How the Body Uses It
Precursor to NAD+/NADP+; pharmacologic doses affect lipids and flushing pathways (GPR109A).
Supplement Origins
Nicotinic acid (flush) and niacinamide/inositol hexanicotinate (no-flush, different effects).
Possible Uses
  • Deficiency (pellagra), specialized lipid therapy (medical)
Long-Term Use
High-dose nicotinic acid requires clinician monitoring.
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Dose Guidance

Studied
14–16 mg/day (RDA); lipid therapy grams/day under medical care
Aspirin or food can blunt flush with nicotinic acid.
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Forms

Nicotinic acid
Standardization varies by product.
Niacinamide (nicotinamide)
Standardization varies by product.
Inositol hexanicotinate (no-flush)
Standardization varies by product.
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Delivery

Coming soon.
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Evidence & Studies

No studies linked yet.
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References

References coming soon.
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Safety & Cautions

Cautions
  • Flushing/itch (nicotinic acid)
  • LFT elevation with high doses
Contraindications
  • Active liver disease (high-dose therapy)
Interactions
No notable interactions recorded.
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