TMG (Trimethylglycine; Betaine)

Plain-language research summary.

DetailDoseFormsDeliveryEvidenceReferencesSafety
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Detail

methylationliverperformance

Methyl donor supporting homocysteine metabolism and liver osmoregulation.

Common Dietary Sources
  • Beets, whole grains, seafood
How the Body Uses It
Donates methyl group to homocysteine via betaine-homocysteine methyltransferase → methionine.
Supplement Origins
Extracted from beets or synthesized.
Possible Uses
  • Homocysteine support
  • Power output (sports studies)
Long-Term Use
Generally well-tolerated; monitor if on methylation-related meds.
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Dose Guidance

Studied
1.5–3 g/day; sports studies often 2.5 g/day
Split dosing optional.
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Forms

Anhydrous betaine (TMG)
Standardization varies by product.
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Delivery

Coming soon.
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Evidence & Studies

No studies linked yet.
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References

References coming soon.
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Safety & Cautions

Cautions
  • GI upset in some
Contraindications
No explicit contraindications listed.
Interactions
No notable interactions recorded.
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